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Sunday, 11 April 2010

Low cholesterol leads to increased cancer rates

This study was published in the American Journal of Epidemiology Vol. 137, No. 9: 966-976

Study title and authors:
Inverse Association between Serum Total Cholesterol and Cancer Mortality in Dutch Civil Servants
Albertine J. Schuit, Carolina E. M. J. Van Dijk, Jacqueline M. Dekker, Evert G. Schouten and Frans J. Kok
From the Department of Epidemiology and Public Health, Agricultural University P.O. Box 238, 6700 AE Wageningen, The Netherlands

The paper can be accessed at: http://aje.oxfordjournals.org/cgi/content/abstract/137/9/966?ijkey=5486e6d4d7c121483ad3c3d69a58d4a098394e1e&keytype2=tf_ipsecsha

The association between cholesterol levels and cancer death was investigated in a study, which lasted 28 years, of 3,091 Dutch civil servants aged 40-65 years and their spouses.

The study found:
(a) Those with the lowest cholesterol had a 110% increased risk of cancer compared to those with the highest cholesterol.
(b) Those with the lowest cholesterol had a 320% increased risk of gastrointestinal cancers compared to those with the highest cholesterol.