Study title and authors:
Statins reduce endogenous dolichol levels in the neuroblastoma cell line SH-SY5Y
Bihter Atil, Evelyn Sieczkowski and Martin Hohenegger
Institute of Pharmacology, Center for Physiology and
Pharmacology, Medical University Vienna, 1090 Vienna, Austria
This study can be accessed at: http://www.biomedcentral.com/2050-6511/13/S1/A51
Dolichols play an important role in biosynthesis, protein metabolism, cell vitality and immune system health.
This study assessed the effects of simvastatin on dolichol levels. The laboratory based study used the human SH-SY5Y cells.
The study found that dolichol levels were significantly decreased by simvastatin.
More information about dolichols, statins and the mevalonate pathway:
The deadly effects statins have on the mevalonate pathway
Statin Damage to the Mevalonate Pathway
Dolichols play an important role in biosynthesis, protein metabolism, cell vitality and immune system health.
This study assessed the effects of simvastatin on dolichol levels. The laboratory based study used the human SH-SY5Y cells.
The study found that dolichol levels were significantly decreased by simvastatin.
More information about dolichols, statins and the mevalonate pathway:
The deadly effects statins have on the mevalonate pathway
Statin Damage to the Mevalonate Pathway