The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Monday, 18 July 2011

Statins impair brain function

This post includes a synopsis of a study published in the American Journal of Medicine 2000 May;108(7):538-46

Study title and authors:
Effects of lovastatin on cognitive function and psychological well-being.
Muldoon MF, Barger SD, Ryan CM, Flory JD, Lehoczky JP, Matthews KA, Manuck SB.
Center for Clinical Pharmacology (MFM), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

This study can be accessed at:

Statin Drugs Side Effects and the Misguided War on Cholesterol
The study investigated the relationship between statins and brain function. 209 generally healthy adults with low-density-lipoprotein (LDL) cholesterol level of 160 mg/dL or higher were randomly assigned to 6-month treatment with lovastatin (20 mg) or placebo. Subjects were given neuropsychological tests before the treatment and at six months.

The study found:
(a) After six months placebo-treated subjects improved on neuropsychological tests in all five performance domains, consistent with the effects of practice on test performance, whereas those treated with lovastatin improved only on tests of memory recall.
(b) Subjects on statins showed a significant worsening of attention and slowing down of thought compared to subjects on placebo.

To conclude: Statins impair brain function.

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