The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Tuesday, 22 November 2011

Statin use increases muscle damage after exercise (including the heart muscle)

This study was published in the American Journal of Cardiology 2011 Oct 27

Study title and authors:
Effect of Statins on Creatine Kinase Levels Before and After a Marathon Run.
Parker BA, Augeri AL, Capizzi JA, Ballard KD, Troyanos C, Baggish AL, D'Hemecourt PA, Thompson PD.
Henry Low Heart Center, Department of Cardiology, Hartford Hospital, Hartford, Connecticut.

This study can be accessed at:

Elevation of creatine kinase levels is an indication of damage to muscle. It is therefore indicative of injuryrhabdomyolysis (kidney damage)heart attackinflammation of the muscles and inflammation of the heart muscle.
The study measured total creatine kinase levels, and the levels of creatine kinase in the heart muscle in 37 subjects treated with statins and 43 nonstatin-treated controls running the 2011 Boston Marathon.

The study found:
(a) The exercise-related increase in creatine kinase 24 hours after exercise, was greater in the statin users than in the controls.
(b) The increase in creatine kinase in the heart muscle 24 hours after exercise was also greater in the statin users than in the controls.
(c) Older runners who were statin users had higher increases in creatine kinase.

To conclude: The results of the study show that statins increase exercise-related muscle injury (including the heart muscle).