The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Friday, 30 April 2010

Statins induce polyneuropathy

This post includes a summary of a paper written in the British Medical Journal 2001;322:1019-1023 and a recipe for beef, courgette and yellow pepper rolls.

Study title and author:
Neuropathy from statins
Elias Ragi,
Malignant Medical Myths: Why MEdical Treatment Causes 200,000 Deaths in the USA each Year, and How to Protect Yourself
Consultant Clinical Neurophysiologist
Royal Devon and Exeter Hospital, Exeter, EX2 5DW

This paper can be accessed at:
Polyneuropathy is a neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously.

The author of the paper, Dr Elias Ragi, is a Consultant Clinical Neurophysiologist from the Royal Devon and Exeter Hospital.

(i) In one year Dr Ragi, reported to the Medicines Control Agency - 16 cases of progressive generalised axonal neuropathy, most likley to have been caused by statins.
(ii) Patients were 52 to 80 years old, mostly males (4:1). Statins were: simvastatin - 5; pravastatin - 4; atorvastatin - 4; cerivastatin - 3.
(iii) Most patients presented with rather progressive weakness or loss of co-ordination in the lower limbs.
(iv) Neuropathy - and its association with statins - was discovered by nerve conduction studies.
(v) In some cases, it is the patient who first suspected the association.
(vi) Weakness occured within two months of instituting, or increasing dosage, of the statin.
(vii) The neuropathy is severe and in several cases leading to loss of nerve supply to the muscle.
(viii) Neuropathy may reverse if the stain is stopped.
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Recipe of the day

Beef, Courgette and Yellow Pepper Rolls
8 thin cut sirloin or minute steaks
Omaha Steaks 7 oz. Top Sirloins
Food Mall: Sirloin Steak
30ml/2tbsp olive oil
1 large yellow pepper, deseeded and cut into strips
2 medium courgettes, cut into matchsticks
60ml/4tbsp fermented soy sauce
Salt and freshly milled black pepper
3 spring onions, cut into long thin strips
60ml/4tbsp sherry or white wine vinegar

1.Place the steaks on a large chopping board, cover with a large piece of cling film or greaseproof paper and flatten well with a rolling pin or meat hammer to about 5mm/¼inch thick. Season.

2.Heat half the oil in a large non-stick frying pan and cook the peppers and courgettes for 2-3 minutes until lightly golden. Add half the fermented soy sauce and cook for a further 30 seconds.

3.Divide the peppers, courgettes and raw spring onions evenly over the steaks. Roll up tightly into bundles and secure with a cocktail stick.

4.Wipe the pan clean and heat the remaining oil. Cook the beef rolls for 4-6 minutes until brown on all sides, removing the cocktail sticks halfway through cooking. Transfer to a plate and keep warm.

5.Add 60ml/4tbsp water to the pan with the remaining fermented soy sauce and vinegar and cook for 1-2 minute until the sauce thickens. Return the beef to the sauce and heat through for a further 2-3 minutes.