The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher
Showing posts with label (apo)C-III. Show all posts
Showing posts with label (apo)C-III. Show all posts

Monday, 4 April 2011

Heart disease risk factors are increased by a diet low in fat and high in carbohydrate

This post features a synopsis on a study published in Circulation 2000;102:1886 and a recipe for garlic pulled pork.

Study title and authors:
VLDL, Apolipoproteins B, CIII, and E, and Risk of Recurrent Coronary Events in the Cholesterol and Recurrent Events (CARE) Trial
Frank M. Sacks, MD; Petar Alaupovic, PhD; Lemuel A. Moye, MD, PhD; Thomas G. Cole, PhD; Bruce Sussex, MD; Meir J. Stampfer, MD, DPH; Marc A. Pfeffer, MD, PhD; Eugene Braunwald, MD
From the Department of Nutrition, Harvard School of Public Health, Boston, Mass (F.M.S., M.J.S.); the Department of Medicine, Harvard Medical School and Brigham and Women’s Hospital, Boston, Mass (F.M.S., M.J.S., M.A.P., E.B.); Oklahoma Medical Research Foundation, Oklahoma City (P.A.); University of Texas School of Public Health, Houston (L.A.M.); Washington University School of Medicine, St Louis, Mo (T.G.C.); and Memorial University of Newfoundland, St John, Newfoundland, Canada (B.S.).

                                                                                                                                           Amazon:
Perfect Health Diet: Four Steps to Renewed Health, Youthful Vitality, and Long LifeMeasurements of  VLDL–apolipoprotein (apo) B, VLDL cholesterol and apoCIII were compared in patients who had either a heart attack or coronary death, with those in patients who did not have a cardiovascular event in 5 years of follow-up.

All factors, when elevated, (1)VLDL–apolipoprotein (apo) B, (2)VLDL cholesterol and (3)apoC-III were associated with heart disease.

All these elevated heart disease factors are associated with a diet low in fat and high in carbohydrate.
VLDL–apolipoprotein (apo) B See here
VLDL cholesterol see here
apoC-III See here

More information on this subject: Books : Scientific Studies : Websites : Videos : Food Mall



Recipe of the day

Garlic Pulled Pork
                                                                                                                                  Buy online:
Coppa - Dry Cured Pork ShoulderIngredients:                 
■1 pork shoulder cut (butt or picnic), weighing 3-4 pounds
■1-2 tablespoons kosher salt
■1/2 teaspoon cumin
■1 teaspoon of black pepper
■1-2 tablespoons of granulated garlic or garlic powder
■optional: 6 fresh garlic cloves, peeled
■The juice of one lime (or sour orange, if you can get one)
■1 onion
■1 bay leaf

Instructions:
Mix together salt, cumin, black pepper and granulated garlic.

Juice the lime over the seasonings and rub the mixture all over the pork.

If you love garlic as much as Pat does, you might want to use fresh garlic, too. Use a knife to slice six thin cuts in the pork and push each clove securely inside each cut. You don’t want the fresh garlic to fall out and touch the cooking vessel or it will burn and affect the flavor of the meat.

The meat should sit out of refrigeration a half hour before you put it in the oven. This ensures that it will cook evenly throughout. If you want to let the meat marinate in the rub longer than this, put it in the fridge for an hour or even overnight.

When you’re ready to cook, preheat the oven to 250 degrees Fahrenheit. Place the roast in a pan with one sliced onion and a bay leaf. Cover and roast for three to four hours, or until the middle of the roast reads about 190 degrees and falls apart easily when pulled with a fork.

Let the roast rest for twenty minutes or so, then uncover. You’ll notice a lot of liquid at the bottom. Use it as a sauce for the meat, which you will now viciously attack with two forks. It’ll fall apart pretty readily, and you’ll get the idea of the shredding method after a couple of pulls. Enjoy!

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Sunday, 3 April 2011

Low fat, high carbohydrate diets increase the risk of heart disease

This post includes a synopsis on a study published in the American Journal of Clinical Nutrition, Vol. 85, No. 6, 1527-1532, June 2007 and a recipe for baked chicken with pomegranate glaze.

Study title and authors:
Increased plasma concentrations of lipoprotein(a) during a low-fat, high-carbohydrate diet are associated with increased plasma concentrations of apolipoprotein C-III bound to apolipoprotein B–containing lipoproteins1,2,3
Min-Jeong Shin, Patricia J Blanche, Robin S Rawlings, Harriett S Fernstrom and Ronald M Krauss
1 From the Children's Hospital Oakland Research Institute, Oakland, CA
                                                                                                                                              Books:
Eating Well for Optimum Health: The Essential Guide to Bringing Health and Pleasure Back to EatingThis study can be accessed at: http://www.ajcn.org/content/85/6/1527.abstract

In this study 140 healthy men consumed for 4 weeks either:
(1) a high-fat, low-carbohydrate diet (HFLC diet 40% fat, 45% carbohydrate)
(2) a low-fat, high carbohydrate diet (LFHC diet 20% fat, 65% carbohydrate)

The study found that concentrations of Lp(a), triglycerides, ApoB, Apo C-III were all higher on the low fat, high carbohydrate diet compared to a high fat, low carbohydrate diet.

All 4 of these values on the low fat, high carbohydrate diet indicate an increased risk of heart disease:
Lp(a) See here
Triglycerides See here
ApoB See here
Apo C-III See here

More information on this subject: Books : Scientific Studies : Websites : Videos : Food Mall


Recipe of the day

Baked Chicken with Pomegranate Glaze

Ingredients:
-1 large lemon                                                                                            Food Mall: Whole Chicken
3 - Organic Whole Chicken 3-3.5# each-2 sprigs fresh rosemary
-1 (5-pound) whole chicken
-2 cups unsweetened pomegranate juice
-1 tablespoon Dijon mustard
-1/2 teaspoon finely chopped garlic
-2 tablespoons plus 1 teaspoon arrowroot
-1/4 teaspoon freshly ground black pepper
-Seeds from 1 pomegranate

Method:
Preheat oven to 375°F.

Pierce lemon in several places with a fork and place whole, along with rosemary, inside chicken cavity.

Tie chicken legs together and place in a roasting pan. Combine juice, mustard, garlic and arrowroot for basting. Pour mixture over chicken, and sprinkle with black pepper. Bake 20 minutes and baste. Bake another 20 minutes, and baste again.

Add pomegranate seeds. Reduce heat to 350°F and bake another hour, basting every 20 minutes.

Pour off liquid and reserve. Let chicken rest 15 minutes under a foil tent. Skim fat off reserved liquid.

Carve chicken and serve with reserved glaze.