Apo B48, chylomicron remnants and heart disease

This post includes a synopsis of a study published in the European Journal of Clinical Investigation 1999 Mar;29(3):204-9 and a recipe for beef and mushroom ragout.

Study title and authors:
Post-prandial chylomicron response may be predicted by a single measurement of plasma apolipoprotein B48 in the fasting state.
Smith D, Watts GF, Dane-Stewart C, Mamo JC.

Department of Medicine, University of Western Australia, Australia.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10202376                   Books:

The clearance from the bloodstream of chylomicron remnants was assessed in male subjects. Elevated levels of chylomicron remnants in the bloodstream are associated with heart disease.

The study found that in the fasting state apo B48 concentration is a marker of chylomicron remnants.

Low fat/high carbohydrate diets cause elevated levels of apo B48. See here.

More information on this subject: Books : Scientific Studies : Websites : Videos : Food Mall

Recipe of the day

Beef and Mushroom Ragout
                                                                                                                                   Food Mall: Steak
Ingredients:

500g shin beef or chuck steak

150g mushrooms, sliced

150g diced bacon
1 large onion, chopped
100ml beef stock
100ml red wine
2 or 3 sprigs thyme
1 tin chopped tomatoes
olive oil

Preparation method
1. Cut the meat into 2 -3 cm cubes.
2. Oil a frying pan and gently cook onions, mushrooms and chopped bacon until onions are soft. Place in slow cooker.
3. Add a little extra oil to the frying pan and brown the meat a few pieces at a time. Place in the slow cooker.
4. Deglaze the pan using the wine and pour into the pot, adding the tomatoes, thyme and stock.
5. Cook on low for 9 hours. Serve with rice and green salad.