Published in Dtsch Arztebl Int 2010; 107(16): 279-85
The Financing of Drug Trials by Pharmaceutical Companies and Its Consequences: Part 1. A Qualitative, Systematic Review of the Literature on Possible Influences on the Findings, Protocols, and Quality of Drug Trials
Schott, G; Pachl, H; Limbach, U; Gundert-Remy, U; Ludwig, W; Lieb, K
Arzneimittelkommission der deutschen Ärzteschaft, Berlin: Dr. med. Schott, Dipl.-Biol. Pachl, Prof. Dr. med. Gundert-Remy, Prof. Dr. med. Ludwig
Klinik für Hämatologie, Onkologie und Tumorimmunologie, HELIOS Klinikum Berlin-Buch:
Prof. Dr. med. Ludwig* Klinik für Psychiatrie und Psychotherapie, Universitätsmedizin Mainz:
Cand. med. Limbach, Prof. Dr. med. Lieb*
This paper can be accessed at: http://www.aerzteblatt.de/int/abstract.asp?id=74342
The study discovered that most drug studies will conclude that the remedy is effective, if the research has been paid for by the manufacturer. The study sponsor influences the result in a variety of ways, concludes Prof Wolf-Dieter Ludwig, chairman of the drug commission of the German Medical Association. Aside from directly paying for the study, the drug company may also have direct, or indirect, financial links with the authors, and this could include payments for lectures, air travel to exotic locations, and the like. The results aren’t the only thing open to bias. The all-important conclusion – the summary that most people focus on – is also open to interpretation, and can even differ from the actual results.
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