Study title and authors:
Serum Cholesterol Levels and the Risk of Parkinson's Disease
Lonneke M. L. de Lau 1 , 2 , Peter J. Koudstaal 2 , Albert Hofman 1 and Monique M. B. Breteler 1
1Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, the Netherlands
2Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands
This study can be accessed at: http://aje.oxfordjournals.org/content/164/10/998.short
The authors examined the association between levels of cholesterol
and the risk of Parkinson's disease among 6,465 subjects aged 55 or more years with 9.4 years of follow-up. The study found:
(a) Those with the highest cholesterol levels, above 7.4 mmol/L (286 mg/dL), had a 45% decreased risk of Parkinson's disease compared to those with the lowest cholesterol, below 5.9 mmol/L (228 mmol/L).
(b) Men with the highest cholesterol levels had a 14% decreased risk of Parkinson's disease compared to men with the lowest cholesterol.
(c) Women with the highest cholesterol levels had a 84% decreased risk of Parkinson's disease compared to women with the lowest cholesterol.
The results of the study show that high cholesterol levels significantly decrease the risk of Parkinson's disease.
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