Study title and authors:
Effects of lovastatin on cognitive function and psychological well-being.
Muldoon MF, Barger SD, Ryan CM, Flory JD, Lehoczky JP, Matthews KA, Manuck SB.
Center for Clinical Pharmacology (MFM), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10806282
 |
| Books: |
The study investigated the relationship between statins and brain function. 209 generally healthy adults with
low-density-lipoprotein (LDL) cholesterol level of 160 mg/dL or higher were randomly assigned to 6-month treatment with lovastatin (20 mg) or placebo. Subjects were given neuropsychological tests before the treatment and at six months.
low-density-lipoprotein (LDL) cholesterol level of 160 mg/dL or higher were randomly assigned to 6-month treatment with lovastatin (20 mg) or placebo. Subjects were given neuropsychological tests before the treatment and at six months.The study found:
(a) After six months placebo-treated subjects improved on neuropsychological tests in all five performance domains, consistent with the effects of practice on test performance, whereas those treated with lovastatin improved only on tests of memory recall.
(b) Subjects on statins showed a significant worsening of attention and slowing down of thought compared to subjects on placebo.
To conclude: Statins impair brain function.
More information on this subject: Books
: Scientific Studies : Other Websites : Videos : Food Mall
