HEALTHY DIETS AND SCIENCE: High fat meals promote higher bioavailability of vitamin K2 compared to low fat meals

The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday 17 August 2011

High fat meals promote higher bioavailability of vitamin K2 compared to low fat meals

This post includes a synopsis of a study published in the Journal of pharmaceutical sciences 1996 Sep;85(9):1012-6 and a recipe for eggs and asparagus.

Study title and authors:
Effect of dietary fat content on oral bioavailability of menatetrenone in humans.
Uematsu T, Nagashima S, Niwa M, Kohno K, Sassa T, Ishii M, Tomono Y, Yamato C, Kanamaru M.
Department of Pharmacology, Gifu University School of Medicine, Japan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8877895

Books:

Vitamin K2 has many beneficial roles including protecting us from heart disease, ensuring healthy skin, forming strong bones, promoting brain function, supporting growth and development and helping to prevent cancer.

The purpose of the study was to determine the effects of fat content on the bioavailability of menatetrenone (vitamin K2).

15 mg of vitamin K2 was administered at breakfast time to healthy male volunteers after meals with three different fat contents (A, 8.8 g; B, 20.0 g; C, 34.9 g) and almost the same calorie content.

The study found:
(a) Vitamin K2 levels were 30% higher after meal B (20.0g fat) compared to the lower fat meal A.
(b) Vitamin K2 levels were 276% higher after meal C (34.9g fat) compared to the lower fat meal A.

To conclude: High fat meals promote higher bioavailability of vitamin K2 compared to low fat meals.

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Recipe of the day

Eggs and Asparagus

Ingredients:

Food Mall: Eggs

3 large eggs

1 tbs butter
1 small green capsicum
6 spears of Asparagus
dash of ground basil, turmeric, paprika, cumin and rosemary

Directions:
(1) Grill green capsicum on each side for about 10 minutes or so. Basically, you want to grill until the skin on each side is dark and blistered for easy removal.

(2) Remove from grill and take out the seeds as well as the blistered skin. Now thinly slice the capsicum.

(3) Grill the asparagus and then add the capsicum.

(4) Fry eggs with butter. Next, combine the herbs and spices then sprinkle all over fried eggs.

Serve eggs together with the grilled asparagus and capsicum.

Fried Egg and Asparagus