The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Thursday, 8 December 2011

Meat and seafood may enhance the quality of life for people with intermittent claudication

This study was published in Vascular Medicine February 2000 vol. 5 no. 1 11-19

Study title and authors:
Nutritional therapy for peripheral arterial disease: a double-blind, placebo-controlled, randomized trial of Heart Bar
Andrew J Maxwell, Barbara E Anderson, John P Cooke
Division of Research and Development, Cooke Pharma, Inc., Belmont, CA, USA

This study can be accessed at:

The study investigated the clinical effects of bars of food enriched in l-arginine in individuals with claudication from atherosclerotic peripheral arterial disease.

41 subjects with intermittent claudication were randomized to three groups: 
(i) two active bars
(ii) one active and one placebo bar
(iii) two placebo bars per day

The study found:
(a) After 2 weeks of treatment, the pain-free walking distance increased 66% while the total walking distance increased 23% in the group taking two active bars/day. The general and emotional/social functioning of the two active bar group also improved. 
(b) After 2 weeks of treatment, beneficial effects were not observed in the one active bar/day and placebo groups.
(c) The beneficial effects of the two active bars/day group were maintained after 10 weeks and, in addition, an improvement in walking distance was observed in the group taking one active bar.

This study shows that l-arginine improves pain-free and total walking distance as well as quality of life in individuals with intermittent claudication.

Rich dietary sources of L-Arginine are turkey, beef, pork, gelatin, wild game, seafood and dairy products.