The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 22 February 2012

High-carbohydrate, low-fat diets increase the risk of heart disease in diabetic patients

This study was published in Diabetes Care 1989 Feb;12(2):94-101

Study title and authors:
Persistence of hypertriglyceridemic effect of low-fat high-carbohydrate diets in NIDDM patients.
Coulston AM, Hollenbeck CB, Swislocki AL, Reaven GM.
Department of Medicine, Stanford University School of Medicine, California.

This study can be accessed at:

Coulston notes that although low-fat high-carbohydrate diets are recommended for patients with diabetes in an effort to reduce the risk of coronary artery disease, the results of short-term studies have shown that these diets can actually lead to an increased risk of heart disease.

In this study Coulston observed the effects of such diets compared to higher-fat diets over a longer period of 6 weeks in diabetic patients.

The diets were either:
  • 60% carbohydrate, 20% protein, 20% fat (high-carbohydrate diet).
  • 40% carbohydrate, 20% protein, 40% fat (high-fat diet).

The study found:
  • The (bad) blood glucose and insulin concentrations were significantly elevated throughout the day when patients consumed the high-carbohydrate diet.
  • The (bad) triglyceride concentrations increased by 30% when patients consumed the high-carbohydrate diet.
  • The (bad) Very low density lipoprotein (VLDL) cholesterol was significantly increased when patients consumed the high-carbohydrate diet.
  • The (good) High density lipoprotein (HDL) cholesterol levels were significantly decreased when patients consumed the high-carbohydrate diet.

This study shows that a high-carbohydrate, low-fat diet increases the risk of heart disease in diabetic patients.