The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 25 April 2012

Analysis of six trials show that as cholesterol levels are lowered the death rate increases

This study was published in the British Medical Journal 1990 Aug 11;301(6747):309-14

Study title and authors:
Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials.
Muldoon MF, Manuck SB, Matthews KA.
Department of Medicine, University of Pittsburgh, PA 15260.

This study can be accessed at:

This study analysed the findings of six cholesterol reduction trials. The participants in the six cholesterol reduction trials received either diet based, drug based, a mixture of diet and drug cholesterol lowering treatment or placebo. The trials lasted for an average of 4.8 years and included 24,847 male participants who were followed for a total of 119,000 person years. The average age of the men was 47.5 years.

The analysis found:
(a) The men receiving cholesterol reduction treatment reduced their cholesterol levels by about 10%.
(b) The men receiving cholesterol reduction treatment had a 7% increase in death rates compared to the men taking a placebo.

The results of this analysis of six trials show that as cholesterol levels are lowered the death rate increases.