The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Sunday, 1 July 2012

How statins cause male infertility

This paper was published in the Journal of Andrology 2005 Jan-Feb;26(1):12

Study title and author:
Atorvastatin and male infertility: is there a link?
Niederberger C.
Division of Andrology, University of Illinois, Chicago, IL, USA.

This paper can be accessed at:

Niederberger notes that some doctors have noticed many men on Lipitor (atorvastatin) have low sperm motility. Sperm motility describes the ability of sperm to "swim" properly towards an egg to enable a successful pregnancy.

Coenzyme Q10 (ubiquinone) is a vitamin-like substance produced by the body.

Niedberger relays how sperm motility may be affected by statins by the following mechanism:
(a) Statins inhibit the production of Coenzyme Q10. Even a brief exposure to atorvastatin causes a marked decrease in blood Coenzyme Q10 concentrations.
(b) Coenzyme Q10 is vital for energy production and is also an important antioxidant. Both these properties are vital for sperm motility.
(c) Coenzyme Q10 is present in high concentrations in semen and high levels of coenzyme Q10 correlate with increased sperm motility.

This paper shows the mechanism of how statins can cause male infertility.