The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 18 July 2012

With only 12 weeks of statin therapy, 36% of the patients have side effects

This study was published in QJM 1999 Jul;92(7):387-94

Study title and authors:
Atorvastatin compared with simvastatin-based therapies in the management of severe familial hyperlipidaemias.
Wierzbicki AS, Lumb PJ, Semra Y, Chik G, Christ ER, Crook MA.
Department of Chemical Pathology, St Thomas' Hospital, London, UK.

This study can be accessed at:

The study investigated the side effects caused by statin therapy (Lipitor). Patients unable to tolerate previous statin therapy were excluded from the study. The trial lasted for 12 weeks and included 201 "patients" with alleged high cholesterol.

The study found:
(a) 36% of patients had to withdraw from the trial because of side effects.
(b) 7% of patients suffered from diarrhoea.
(c) 5% of patients developed an erythematous rash (An erythematous rash is characterized by redness resulting from skin inflammation surrounding a patch of skin where a rash is located).
(d) 4% of patients suffered from joint pains.

After only 12 weeks of statin (Lipitor) therapy, over a third of the patients had to withdraw from the trial because of side effects.

Useful book: How Statin Drugs Really Lower Cholesterol: And Kill You One Cell at a Time