The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Saturday, 29 September 2012

Analysis of 72 trials shows that statins increase the risk of diabetes by 9%

This study was published in QJM 2012 Feb;105(2):145-57

Study title and authors:
Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.
Alberton M, Wu P, Druyts E, Briel M, Mills EJ.
Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.

This study can be accessed at:

This paper sought to identify different risk effects of statin therapy. The paper analysed seventy-two trials involving 159,458 patients.

The paper found:
(a) Statin users had a 9% increased risk of diabetes compared to non-users.
(b) Statin users had a 31% increased risk of elevated aspartate aminotransferase levels compared to non-users. (Elevated levels of aspartate aminotransferase indicate damage to liver, heart, muscle, kidney and brain tissues).
(c) Statin users had a 28% increased risk of elevated alanine aminotransferase levels compared to non-users. (Elevated levels of alanine aminotransferase indicate liver damage).

The data from this analysis of 72 trials shows that statins increase the risk of diabetes by 9%.