The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Friday, 30 November 2012

High-fat diets reduce inflammation compared to low fat diets

Forsythe CE, Phinney SD, Fernandez ML, Quann EE, Wood RJ, Bibus DM, Kraemer WJ, Feinman RD, Volek JS.
Department of Kinesiology, University of Connecticut, 2095 Hillside Road, Unit 1110, Storrs, CT, 06269-1110, USA.

This study can be accessed at:

Inflammation is an important risk factor in metabolic syndrome, diabetes and heart disease. This study tested the effects of low-fat and high-fat diets on markers of inflammation. This was a 12 week randomised, controlled, dietary intervention trial and included 40 overweight men and women, aged 18-55 years.

The subjects consumed diets of either:
(i) 12% carbohydrate, 59% fat, 28% protein. (High-fat diet).
(ii) 56% carbohydrate, 24% fat, 20% protein. (Low-fat diet).

The study found there was an overall greater anti-inflammatory effect associated with the high-fat diet, as evidenced by greater decreases in inflammatory markers such as: Tumor necrosis factor-alpha, interleukin 6, interleukin 8, monocyte chemotactic protein-1, E-selectin, intercellular adhesion molecules, and plasminogen activator inhibitor-1.

The results of the study reveal that a high-fat diet reduces inflammation compared to a low fat diet.