The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Monday, 19 November 2012

Low levels of LDL cholesterol increase the risk of gallstone disese

This study was published in the Journal of Hepatology 2012 Aug 21
Study title and authors:
Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses.
Stender S, Frikke-Schmidt R, Benn M, Nordestgaard BG, Tybjærg-Hansen A.
Department of Clinical Biochemistry, Rigshospitalet, Denmark; Copenhagen University Hospitals, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
This study can be accessed at:

This study investigated the association of low density lipoprotein (LDL) cholesterol levels with gallstone disease. The study included 63,051 individuals. The individuals were divided into five groups based on their LDL cholesterol levels. The highest group had 134% higher LDL cholesterol levels than the lowest group.

The study found that those with the lowest LDL cholesterol levels had a 6% increased risk of gallstone disease compared to those with the highest LDL cholesterol levels.