This study was published in the Journal of Clinical Endocrinology and Metabolism 1998 Jul;83(7):2309-12
Study title and authors:
Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake.
Miller KK, Parulekar MS, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon SK.
Neuroendocrine Unit, Massachusetts General Hospital, Boston 02114, USA.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9661600
This study investigated factors that may lead to hypothalamic amenorrhea (hypothalamic amenorrhea is a condition in which menstruation stops for several months due to a problem involving the hypothalamus). The study included 21 women with hypothalamic amenorrhea who were compared with 30 age-, weight-, and body fat-matched women with normal menstruation.
Regarding fat intake, the study found that women with hypothalamic amenorrhea consumed 48% less fat than women with normal menstruation.