The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 9 January 2013

Antiphospholipid antibodies (indicate an increased risk of blood clots or pregnancy loss) are associated with statin use

This study was published in the Journal of Clinical Pathology 2012 Jun;65(6):551-6
Study title and authors:
High antiphospholipid antibody levels are associated with statin use and may reflect chronic endothelial damage in non-autoimmune thrombosis: cross-sectional study.
Broder A, Tobin JN, Putterman C.
Division of Rheumatology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York, USA.
This study can be accessed at:

Persistently elevated antiphospholipid antibodies and positive lupus anticoagulant are associated with an increased risk of thrombosis and pregnancy loss, see here and here.

The study explored whether antiphospholipid antibodies and positive lupus anticoagulant were associated with statin use in 270 patients without autoimmune diseases hospitalised with arterial or venous thrombosis (blood clots).

The study found that statin users were 220% more likely to have antiphospholipid antibody positivity.