The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Monday, 3 June 2013

Long-term statin treatment may be associated with chronic peripheral neuropathy

This paper was published in the European Journal of Clinical Pharmacology 1999 Jan;54(11):835-8
Study title and authors:
Statins and peripheral neuropathy.
Jeppesen U, Gaist D, Smith T, Sindrup SH.
Department of Neurology, Odense University Hospital, Denmark.
This paper can be accessed at:

This paper reports of seven cases of peripheral neuropathy associated with long-term statin therapy.

(i) Diagnosis of neuropathy by statin therapy was confirmed after all other causes of neuropathy were thoroughly excluded.
(ii) Neuropathy symptoms manifested up to seven years after initiation of statin therapy.
(iii) In all seven cases the neuropathy affected the nerve fibres and with affection of both thick and thin nerve fibers.
(iv) The symptoms of neuropathy persisted during an observation period lasting from 10 weeks to one year in four cases after statin treatment had been withdrawn.

Jeppesen concluded: "Long-term statin treatment may be associated with chronic peripheral neuropathy".