The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Monday, 29 July 2013

Doctor says there is no evidence that statins are safe

This paper was published in the Canadian Medical Association Journal May 6: 2008

Study title and author:
Statins - Safe?
Dr Herbert H. Nehrlich

This paper can be accessed at:

Dr Nehrlich, a doctor from Australia, discusses the effects of statin drugs.

(i) Statins reduce the body's production of mevalonate through the suppression of a liver enzyme called hydroxymethylglutaryl (HMG) coenzyme A reductase.
(ii) This enzyme is crucial in enabling the body to synthesize such substances as cholesterol, Co-enzyme Q-10 etc., substances that are essential for every living cell.
(iii) So, if you reduce the supply of mevalonate, the liver can no longer keep up production of sufficient cholesterol and has to slow the shipping of cholesterol from the depot (liver) to the various areas in need of it via the bloodstream. Hence, blood cholesterol will be lower in lab tests.
(iv) Mevalonate is not just important in this respect but is heavily involved in muscle metabolism as well as in the production of thromboxane. Thromboxane, of course, is the agent responsible for the important stage in healing called clotting and originates in the platelets of our blood.
(v) Mitochondria are energy factories that MUST have coenzyme Q- 10, the very substance that is in short supply when people undergo statin treatment.
(vi) The dismal success record of statin treatment, combined with their sometimes atrocious side effects (identified and hidden) makes the prescription of statins in humans an assault with unknown and likely dire consequences.
(vii) People tend to die with low cholesterol blood levels.
(viii) May I ask for the studies that have shown that lowering cholesterol is reasonable and thus good practice? Statins are safe? Let us look at the PROSPER Trial and the all cause mortality. It is not improved by statins.
(ix) I prefer to see cholesterol as an extremely vital substance, essential for good health and indispensable when it comes to repair and maintenance of the body.
(x) Statins are now Big Pharma's golden goose and the price of gold is rising.
(xi) If we think of rhabdomyolysis, of transient global amnesia and of the propensity of statins to initiate cancer in many animals, if we consider the truly dismal success of statin treatment then we can skip looking at the plausibility of using these drugs altogether.
(xii) Statins are mayhem to Coenzyme Q-10 and it follows that statins may thus weaken the heart. They may cause cancer in humans.

Dr Nehrlich concludes: "There is no evidence that statins are safe".