The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 22 October 2014

Statins have a significant negative impact on quality-of-life

This study was published in Pharmacotherapy 2009 Jul;29(7):800-11
Study title and authors:
Statin-associated adverse cognitive effects: survey results from 171 patients.
Evans MA, Golomb BA.
Department of Medicine, University of California-San Diego, La Jolla, California 92093-0995, USA.
This study can be accessed at:

The objective of the study was to characterize the adverse cognitive effects of statins. In the study, a survey was completed by 171 patients (age range 34-86 yrs) who had self-reported memory or other cognitive problems associated with statin therapy.

The study found:
(a) Of 143 patients who reported stopping statin therapy, 128 (90%) reported improvement in cognitive problems, sometimes within days of statin discontinuation.
(b) In some patients, a diagnosis of dementia or Alzheimer's disease reportedly was reversed.
(c) 19 patients whose symptoms improved or resolved after they discontinued statin therapy and who underwent rechallenge with a statin exhibited cognitive problems again (multiple times in some).
(d) Higher potency statins led to higher rates of cognitive-specific adverse drug reaction.
(e) Quality of life was significantly adversely affected.

Evans concludes: "Findings from the survey suggest that cognitive problems associated with statin therapy have variable onset and recovery courses, a clear relation to statin potency, and significant negative impact on quality-of-life".