The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Tuesday, 10 March 2015

Statins increase the risk of diabetes by 46%

This study was published in Diabetologia DOI 10.1007/s00125-015-3528-5

Study title and authors:
Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort
Henna Cederberg & Alena Stančáková & Nagendra Yaluri & Shalem Modi & Johanna Kuusisto & Markku Laakso
Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital

This study can be accessed at:

The aim of this work was to investigate the mechanisms underlying the risk of type two diabetes associated with statins. The study included 8,749 non-diabetic men, aged 45–73 years, who were followed up for 5.9 years.

The study found:
(a) Individuals taking statins had a 46% increased risk of developing diabetes compared to individuals not taking statins.
(b)  Insulin sensitivity was decreased by 24% in individuals on statin treatment compared with individuals without statin treatment.
(c)  Insulin  secretion was decreased by 12% in individuals on statin treatment compared with individuals without statin treatment.

Cederberg concluded: "Statin treatment increased the risk of type 2 diabetes by 46%, attributable to decreases in insulin sensitivity and insulin secretion".