Damaging effects of gliadin on three-dimensional cell culture model
Ersilia Dolfini, Luca Elli, Leda Roncoroni, Barbara Costa, Maria Pia Colleoni, Vito Lorusso, Simona Ramponi, Paola Braidotti, Stefano Ferrero, Maria Letizia Falini, Maria Teresa Bardella
Ersilia Dolfini, Leda Roncoroni, Department of Biology and Genetics for Health Sciences, University of Milan, Milan, Italy
Luca Elli, Maria Teresa Bardella, Department of Gastroenterology, University of Milan, Ospedale Maggiore Policlinico, Mangiagalli e
Regina Elena IRCCS, Milan, Italy Barbara Costa, Department of Biotechnology and Bioscience, University of Milan-Bicocca, Milan, Italy
Maria Pia Colleoni, Department of Pharmacology, Chemotherapy and Toxicology, University of Milan, Milan, Italy
Vito Lorusso, Simona Ramponi, Bracco Imaging SpA, Milan Research Centre, Milan, Italy
Paola Braidotti, Stefano Ferrero, Department of Medicine, Surgery and Dentistry, S. Paolo Hospital and Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena IRCCS, Milan, Italy
Maria Letizia Falini, Department of Agrifood Molecular Science, University of Milan, Milan, Italy
This paper can be accessed at: http://www.wjgnet.com/1007-9327/11/5973.pdf
Glutathione helps to keep human cells healthy and their chemical reactions in balance.
Gliadin reduced the content of Glutathione in cells by 20%.
The data from the paper clearly demonstrates that gliadin (gluten protein) has a direct damaging effect
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