The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Tuesday, 27 July 2010

Statins associated with pancreatitis

This post includes a synopsis of a paper published in Pharmacotherapy Volume: 26 Issue: 3 March 2006 Page(s): 414-422

Study title and authors:
A Case of Simvastatin-Associated Pancreatitis and Review of Statin-Associated Pancreatitis
Jeremy L Johnson, Pharm.D 1 1 Ilana B. Loomis, Pharm.D 2
1Department of Pharmacy: Clinical and Administrative Sciences, College of Pharmacy, University of Oklahoma Schusterman Center, Tulsa, Oklahoma.
2College of Pharmacy, University of Oklahoma Health Sciences Center, University of Oklahoma, Oklahoma City, Oklahoma.

This paper can be accessed at:

This paper describes the case of a middle-aged man who developed pancreatitis after taking statins.

(i) A 58-year-old man who was hospitalized with idiopathic pancreatitis 4 months after starting simvastatin therapy.

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(ii) He stopped the statins and was discharged from hospital after five days.
(iii) He restarted simvastatin therapy and was again admitted to hospital 16 months later with a second diagnosis of acute pancreatitis.
(iv) He stopped the statins and was discharged from hospital after three days.
(v) Simvastatin was restarted on discharge, but the patient stopped taking it after experiencing muscle soreness and weakness in his arms.
(vi) He recalled having similar arm pain that preceded the previous episode of acute pancreatitis.
(vii) All other causes of the pancreatitis had been ruled out; thus, the correlation between simvastatin-induced muscle pain and onset of acute pancreatitis on two separate occasions made simvastatin the suspected instigating agent.

This case highlights the association between statins and pancreatitis.

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