The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 26 January 2011

The elderly die earlier when taking statins

This post contains a summary of a study published in Age Ageing 2010 39 (6): 674-680 and a recipe for braised beef with madeira sauce.

Study title and authors:
Lipid-lowering treatment to the end? A review of observational studies and RCTs on cholesterol and mortality in 80+-year olds
$29 Billion Reasons to Lie About Cholesterol
Line Kirkeby Petersen1, Kaare Christensen1 and Jakob Kragstrup2
1Research Unit of Epidemiology, Danish Aging Research Center and
2Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, Odense, Denmark

This paper can be accessed at:
The author reviewed a total of 12 studies regarding the relationship of cholesterol levels and all-cause mortality. This corresponded to 13,622 participants: 3,789 aged 80 and above in eight studies and 9,833 aged 71103 (average age 78 years) in four studies.

The review found:
(a) Regarding all-cause mortality in the 80+-year olds, low cholesterol levels did not seem beneficial in any study and low cholesterol levels (less than 5.5 mmol/l or 212 mg/dL) is associated with increased mortality among 80+-year olds.
(b) There was no evidence that statins decrease all-cause mortality in elderly people without known vascular disease, on the contrary, it was even possible that statins increased all-cause mortality.

This finding of the review show that low cholesterol and possibly statin treatment increases the death rate in the elderly.

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall

Recipe of the day

Braised Beef with Madeira Sauce
Organic Grass Fed Brisket Roast ONE (2 to 3 lb. Roast)
Food Mall: Beef Brisket
1.3kg/3lb brisket
Salt and freshly milled black pepper
75g/3oz bacon, roughly chopped or bacon lardons
6 shallots, peeled and finely chopped
2 garlic cloves, peeled and crushed
45ml/3tbsp olive oil
1 small bunch fresh herbs
3 parsnips, peeled and chopped
4 celery sticks, chopped
450ml/¾pint good, hot beef stock
450ml/¾pint Madeira wine

1.Place the joint on a chopping board and season.

2.Heat a large non-stick frying pan and cook the bacon, shallots and garlic for 3-4 minutes. Transfer to a large ovenproof casserole dish.

3.In the same frying pan heat the oil and brown the joint on all sides for 4-5 minutes and transfer to the dish.

4.Add the remaining ingredients, cover the dish with 2 sheets of greaseproof paper or foil and secure with a lid.

5.Bring to the boil, reduce the heat and cook on the hob for the calculated cooking time until the beef is tender.

6.Remove the joint from the pan, transfer to a warm plate, cover and rest for 10 minutes before slicing. Meanwhile add olive oil to the sauce and stir gently. - 468x60