Study title and authors:
Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease.
Reitz C, Tang MX, Schupf N, Manly JJ, Mayeux R, Luchsinger JA.
Gertrude H. Sergievsky Center, Columbia University, New York, NY 10032, USA. cr2101@columbia.edu
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21149810
The study examined the association of cholesterol levels with Alzheimer disease. The study included 1,130 men and women (who were free of cognitive impairment at the start of the study) aged 65 or over with 4,469 person-years of follow-up.
The study found:
(a) Those with the highest total cholesterol levels had a 20% decreased risk of developing Alzheimers compared to those with the lowest total cholesterol levels.
(b) Those with the highest high density lipoprotein (HDL) cholesterol levels had a 60% decreased risk of developing Alzheimers compared to those with the lowest high density lipoprotein (HDL) cholesterol levels.
(c) Those with the highest low density lipoprotein (LDL) cholesterol levels had a 10% decreased risk of developing Alzheimers compared to those with the lowest loe density lioprotein (LDL) cholesterol levels.
The results of the study show that high levels of total cholesterol, HDL cholesterol LDL cholesterol are associated with a decreased risk of Alzheimers disease
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