Study title and authors:
Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15525560
Clofazimine is an antibiotic and is potentially useful for the treatment of disease due to multidrug resistant Mycobacterium tuberculosis, as well as leprosy and certain chronic skin diseases. The study was conducted to explore issues relating to bioavailability in the presence of food, orange juice, and antacid.
The authors concluded administration of clofazimine with a high fat meal provides the greatest bioavailability. Both orange juice and aluminum-magnesium antacid produced a reduction in mean bioavailability of clofazimine.
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Recipe of the day
Italian Veal Chops
|Food Mall: Veal Chops|
2 garlic cloves, minced
1 can (1 lb. 12 oz) tomatoes
In skillet, brown chops. Season with pepper. Sprinkle with oregano and parsley. Add garlic and tomatoes. Cover and simmer until tender, about 2 hours.
|Italian Veal Chops|