The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Thursday, 14 July 2011

The connection between high carbohydrate diets, high blood sugar levels and heart disease

This post includes a synopsis of a study published in Diabetes Care November 16, 2009 and a recipe for peppered beef.

Study title and authors:
Inflammation markers and metabolic characteristics of subjects with one-hour plasma glucose levels
Gianluca Bardini, MD, PhD, Ilaria Dicembrini, MD, Barbara Cresci, MD and Carlo Maria Rotella, MD (
Section of Endocrinology, Department of Clinical Pathophysiology, University of Florence, Italy

This study can be accessed at:

Inflammation, insulin resistance and metabolic syndrome have been shown to be risk factors for heart disease. See here and here.
Trick And Treat - how 'healthy eating' is making us ill

The study examined the relationship between 1-hour blood glucose levels and inflammation, insulin resistance and metabolic syndrome. 1,062 subjects were enrolled and had a oral glucose load test. The study then compared those who had 1-hour blood glucose levels above 155 mg/dl with those whose 1-hour blood glucose levels were below 155 mg/dl.

The study found:
(a) Subjects with 1-hour blood glucose levels above 155 mg/dl showed a significant increase in inflammation compared to subjects with 1-hour blood glucose levels below 155 mg/dl.
(b) Subjects with 1-hour blood glucose levels above 155 mg/dl showed a significant increase in insulin resistance compared to subjects with 1-hour blood glucose levels below 155 mg/dl.
(c) 100% of the subjects with 1-hour blood glucose levels above 155 mg/dl had metabolic syndrome, whereas only 31% of the subjects with 1-hour blood glucose levels below 155 mg/dl.

Bardini notes how the study shows that high blood sugar levels (over 155 mg/dl) could be considered a new “marker” for heart disease risk.

High blood sugar is caused by eating foods with a high glycemic load such as cornflakes, coco pops, special K, grape nuts, bagels, dried dates, rice, buckwheat, macaroni, spaghetti and potatoes.

Foods with a low glycemic index maintain healthy blood sugar levels. Foods such as meat, poultry, fish, cheese, or eggs have a glycemic index of zero.

To conclude: Diets high in carbohydrates lead to high blood sugar levels which are a marker for heart disease risk.

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall 

Recipe of the day

Peppered Beef
Omaha Steaks Sirloin Roasts
Food Mall: Sirloin Roast Beef
1.3kg/3lb sirloin, or topside joint
1 large garlic cloves, peeled and finely chopped
15ml/1tbsp mixed peppercorns, crushed
50ml/2floz good quality balsamic vinegar

1.Place the garlic, peppercorns, salt and vinegar in a large non-metallic shallow dish and mix well.

2.Add the beef to the marinade mixture and coat well. Cover and refrigerate overnight.

3.Preheat the oven to Gas mark 4-5, 180-190°C, 350-375°F.

4.Remove the joint from the marinade and transfer to a metal rack in a large non-stick roasting tin and open roast for the preferred, calculated cooking time, basting occasionally with any meat juices. Cover with foil if browning too quickly.

5.Remove the joint from the tin and transfer to a warm platter. Cover and set aside to rest for 15-20 minutes.

6.Carve the joint and serve.

Peppered Beef