The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 21 December 2011

Women should not be prescribed statins as they fail to provide any overall health benefit

This article was published in the British Medical Journal 2007 May 12; 334(7601): 983

Study title and author:
Malcolm Kendrick, general practitioner
24 Prestwick Close, Tytherington, Macclesfield, Cheshire SK10 2TH

This paper can be accessed at:

Dr. Kendrick believes there is little or no evidence of health benefits for women taking statins.
He makes the following observations:
(a) To date, none of the large trials of secondary prevention with statins has shown a reduction in overall mortality in women.
(b) The primary prevention trials have shown neither an overall mortality benefit, nor even a reduction in cardiovascular end points in women.
(c) Women should not be prescribed statins. Not only do statins fail to provide any overall health benefit in women, they represent a massive financial drain on health services. This money could be diverted to treatments of proved value.
(d) Statins carry a substantial burden of side effects.
(e) Mass medicalisation is a dangerous road with many psychological and societal consequences.
(f) In the Scandinavian simvastatin survival study three more women died taking statins than the women who took the placebo.
(g) In the studies of primary prevention neither total mortality nor serious adverse events have been reduced.
(h) A meta-analysis published in the Lancet found that statins even failed to reduce coronary heart disease events in women.
(i) Another meta-analysis of statins in primary prevention suggested that overall mortality may actually be increased by 1% over 10 years (in both men and women).
(j) Data from 124,814 women in 19 studies and trials found that cholesterol levels had no impact on total death rates and heart disease.
(k) Studies have suggested that side effects from statins may be much more common than is recognised.
(l) One study found that 80% of athletes could not tolerate statins.
(m) Research by Golomb and McGraw found that doctors often dismiss most (probable) statin related events. Patients who met the criteria for definite or probable adverse events reported that their doctors tended to dismiss symptoms, deny specific statins adverse events, and failed to appreciate the effect of the adverse reaction on their quality of life.
(n) More evidence comes from the US Food and Drug Administration adverse event reporting system. Between November 1997 and May 2004 simvastatin was reported as a direct cause of 49,350 adverse events and 416 deaths.Adverse events are greatly under-reported, so the actual figures are likely to be much higher.
(o) Of further concern, as statins are increasingly prescribed to younger women, is the potential for birth defects, with severe neurological abnormalities reported. Spending millions on a treatment that has no proved benefit and may cause serious harm goes against the rationale of evidence based prescribing.
Women should not be prescribed statins as they fail to provide any overall health benefit.