The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Sunday, 10 March 2013

Paranoia may be an adverse effect due to statin therapy

This paper was published in the American Journal of Geriatric Pharmacotherapy 2008 Mar;6(1):28-32
Study title and authors:
Behavioral changes with paranoia in an elderly woman taking atorvastatin.
Peters JT, Garwood CL, Lepczyk M.
Department of Pharmacy Practice, Wayne State University, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan 48201, USA.
This paper can be accessed at:

This paper reports of behavioral changes in a patient taking atorvastatin.

(i) A 79-year-old woman developed paranoia, anxiety, and behavioral changes approximately 2.5 weeks after starting atorvastatin at 10 mg per day.
(ii) After two months of therapy, the patient discontinued atorvastatin, and her symptoms fully resolved after four days.

This report emphasizes the possibility of paranoia as a central nervous system adverse effect due to statin therapy.