Study title and authors:
Effect of Coenzyme Q10 on Myopathic Symptoms in Patients Treated With Statins
This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17493470
Caso notes that statin use is often associated with a variety of muscle-related pain (myopathies). Myopathy may be related in part to statin inhibition of the synthesis of coenzyme Q10, an essential cofactor for mitochondrial energy production.
The aim of this study is to determine whether coenzyme Q10 would reduce the degree of muscle pain associated with statin treatment. Patients with myopathic symptoms were randomly assigned (for 30 days) in a double-blinded protocol to treatment with either:
(i) Coenzyme Q10 (100 mg per day, 18 patients)
(ii) Vitamin E (400 IU per day, 14 patients).
The study found:
(a) Pain severity decreased by 40% and pain interference with daily activities decreased by 38% in the group treated with coenzyme Q10.
(b) In contrast, no changes in pain severity or pain interference with daily activities was observed in the group treated with vitamin E.
The results of the study suggest that statin treatment is associated with muscle pain by inhibiting the synthesis of coenzyme Q10.
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Recipe of the day
Irish lamb stew
1-2 pounds lamb, cut up
3-4 yellow onions, cut into 1/2" pieces
|Food Mall: Lamb|
1-2 bay leaves
1/2-1 t. dried tarragon
1/2-1 t. ground black pepper
Combine the above ingredients in a crockpot with enough water to barely cover.
Cook overnight on low (slower cooking lets the veggies flavor through without getting mushy).
Allow to cool in order to easily remove the excess fat, the bones, and the bay leaves.
Reheat to serve.