The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Wednesday, 21 April 2010

Statin treatment lowers the energy producing nutrient coenzyme Q10

This post includes a summary of a study published in the Journal of Clinical Pathology 1993 Nov;46(11):1055-7 and a recipe for Thai hot and sour shrimp soup.

Study title and authors:
Statin Drugs Side Effects and the Misguided War on Cholesterol
Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin.
Watts GF, Castelluccio C, Rice-Evans C, Taub NA, Baum H, Quinn PJ.
Department of Endocrinology and Chemical Pathology and Public Health Medicine (UMDS), St Thomas's Hospital, London.

This study can be accessed at:

Watts notes that coenzyme Q10 is essential for mitochondrial function (energy production) and antioxidant activity.

This study assessed the effects of statin treatment on coenzyme Q10 levels. The study included:
(i) 20 patients with "high" cholesterol treated with a low-fat diet and simvastatin.
(ii) 22 patients with "high" cholesterol treated with a low-fat diet alone.
(iii) 20 normal controls. (Normal diet).

The study found:
(a) Patients treated with simvastatin had a significantly lower coenzyme Q10 levels than either patients receiving diet alone or normal controls.
(b) The higher the dose of simvastatin, the lower the coenzyme Q10 levels.

Watts concludes: "We suggest that a reduction in plasma coenzyme Q10 may underpin some of the severe side-effects of statins... a reduction in coenzyme Q10 may also compromise the course of coronary atherosclerosis... we recommend that consideration be given to measuring plasma coenzyme Q10 in patients receiving statins and particularly in those with clinically important cardiac disease".

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall 

Recipe of the day

Thai Hot and Sour Shrimp Soup

1 tablespoon olive oil
Shells from shrimp (see below)
8 cups chicken stock
3 stalks lemon grass, cut into 1" lengths
4 kaffir lime leaves
1 teaspoon lime zest
2 green Serrano chiles, slivered
2 pounds fresh shrimp, approximately 20 count per pound, shelled and deveined
Peeled & Deveined Jumbo Shrimp (2 Lbs)
Food Mall: Deveined Shrimp
1 tablespoon coconut milk
1/2 teaspoon salt
juice of 2 limes
1 red Serrano chili, slivered
2 tablespoons coriander leaves (cilantro), coarsely chopped
3 green onions (including some green), coarsely chopped

Heat the oil in a saucepan and fry the shells until they turn pink.

Add the chicken stock, lemon grass, lime leaves, lime rind,and green chilis.

Bring to a boil, cover, reduce heat and simmer for 20 minutes.

Strain the mixture through a sieve, return the liquid to a saucepan and bring to a boil.

Add the shrimp to this boiling "stock" and cook them for 2-3 minutes.

Reduce heat to simmer and add the coconut milk, salt and lime juice. Stir and immediately remove from heat to prevent overcooking.

Pour the soup in a tureen or ladle into bowls, sprinkle with red chilis, coriander leaves and green onions.

Serve piping-hot.