Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function.
D L Eizirik, G S Korbutt, and C Hellerström
Department of Medical Cell Biology, Uppsala University, Sweden.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC443168/?tool=pmcentrez
The results of the study suggest that lasting exposure to high glucose concentrations from a high carbohydrate diet damages the function of human pancreatic islets, which can lead to diabetes.
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