The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher
Showing posts with label Angiotensin Receptor Blockers (ARBs) and Birth Defects. Show all posts
Showing posts with label Angiotensin Receptor Blockers (ARBs) and Birth Defects. Show all posts

Thursday, 31 March 2011

Angiotensin II receptor blockers (ARBs) must not be taken if planning a pregnancy

This post includes a synopsis of a study published in Reproductive Toxicology Volume 28, Issue 1, July 2009, Pages 109-112 and a recipe for pork tenderloin with cilantro pesto.

Study title and authors:
Angiotensin II receptor blockers in pregnancy: A report of five cases
Ksenija Gersak, a, Marta Cvijica and Lilijana Kornhauser Cerara
aDepartment of Obstetrics and Gynaecology, University Medical Centre Ljubljana, Slajmerjeva 3, SI-1000 Ljubljana, Slovenia

This paper can be accessed at: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TC0-4VP667H-2&_user=10&_coverDate=07%2F31%2F2009&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1686101007&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=edfb6af47f5e67d4671a7f2d024600ab&searchtype=a

The study examined the effects of angiotensin II receptor blockers (ARBs) received in pregnancy on the fetus. High blood pressure medication was given to 346 pregnant women. ARBs were given in only five pregnancies.                                                                                                                  Books:
Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs

Two women delivered healthy babies at term; another term baby had one additional finger and toe. Other two pregnancies were complicated with a deficiency of amniotic fluid and ended in preterm delivery. One preterm infant had abnormal kidney function tests.

Gersak advises that women should be informed that ARB-antihypertensive therapy must be replaced/stopped before planning their pregnancy or at least as soon as the pregnancy is confirmed.

More information on this subject: Books : Scientific Studies : Websites : Videos : Food Mall 


Recipe of the day

Pork Tenderloin with Cilantro Pesto

Marinade Ingredients:
■2 pounds of pork tenderloin
■4 tablespoons olive oil                                                                            Food Mall: Pork Tenderloin
All Natural Pork Tenderloin Roast 2-1.25 lb■2 teaspoons sesame oil
■2 tablespoons rice wine vinegar
■2 cloves of garlic, chopped
■1 inch fresh ginger, peeled and chopped

Instructions:
Slice the tenderloin into rounds of 1-inch thickness. Mix oils and vinegar, add garlic and ginger.

Marinate the pork slices in a non-reactive glass container for at least 2 hours or overnight, turning at intervals to marinate both sides of the slices. When the pork is ready to cook, prepare the pesto below:

Pesto Ingredients:
■1 bunch of cilantro, leaves only
■2 large garlic cloves
■1-inch piece of ginger, peeled and sliced thin
■1 tablespoon fish sauce
■1/4 cup olive oil (or less, to taste)
■1 teaspoon sesame oil (or more, to taste)
■1/4 cup almond butter
■1 teaspoon honey (optional)
■1/2 -1 cup coconut milk
■sea salt to taste

Blend sauce ingredients in blender or food processor until smooth, adding coconut milk until preferred consistency is reached.

To cook the pork, heat some coconut oil, lard, or olive oil in a large skillet over medium-high heat. Quickly sear the slices, turning once, until just cooked through. Do not crowd the pan, cook in batches as needed so they sear and don’t steam.

Keep each batch warm in a warm oven or covered in foil wrap.

To serve: Put a few slices of pork on a plate with a little bit of pesto on each slice, or serve pesto on the side. (A little pesto goes a long way, flavor-wise.)

Serve with cooked greens with sesame seeds and sliced red peppers for a nice color combo.

Wednesday, 30 March 2011

ACE inhibitors and ARBs linked to serious birth defects

This post includes a synopsis on a study published in Early Human Development Volume 82, Issue 1, Pages 23-28 (January 2006) and a recipe for a fried egg.

Study title and authors:
Fetopathy associated with exposure to angiotensin converting enzyme inhibitors and angiotensin receptor antagonists
Albert Quan
Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9063, USA

This paper can be accessed at: http://www.earlyhumandevelopment.com/article/S0378-3782(05)00268-9/abstract

Angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) both control high blood pressure.
                                                                                                                                              Books:
Before You Take that Pill: Why the Drug Industry May Be Bad for Your HealthAngiotensin receptor blockers include:
•candesartan (Atacand)
•eprosartan (Teveten)
•irbesartan (Avapro)
•telmisartan (Micardis)
•valsartan (Diovan)
•losartan (Cozaar)
•olmesartan (Benicar)

Quan reports that the use of ACE inhibitors and ARBs in pregnant women revealed serious side effects on fetal development including kidney failure, kidneys not developing correctly, low blood pressure, fetal urinary tract malformations, incomplete development of the lungs and underdeveloped skull cap.

Quan recommends that angiotensin converting enzyme inhibitors and angiotensin receptor blockers should be avoided in all pregnant women.

More information on this subject: Books : Scientific Studies : Websites : Videos : Food Mall 


Recipe of the day
                                                                                                                              Food Mall: Eggs
3 Dozen Fresh Farm EggsFried Egg
Ingredients:
1 egg
1tb butter

Instructions:
Melt butter in a heavy skillet over a medium flame and crack the egg into the pan.

Cover with a lid and cook gently for several minutes until the white becomes firm and the yolk somewhat thickened.

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