A milligram of gluten a day stops a celiac patient from recovering

Published in Nutr Rev. 2004 Sep;62(9):360-3.

A milligram of gluten a day keeps the mucosal recovery away: a case report.
Biagi F, Campanella J, Martucci S, Pezzimenti D, Ciclitira PJ, Ellis HJ, Corazza GR.
IRCCS Policlinico S Matteo, University of Pavia, Italy.

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15497770
 
The author reports a case of a celiac patient in whom the ingestion of a milligram of gluten every day for 2 years prevented recovery.
 
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Gluten can cause intestinal damage in celiacs AND non-celiacs

Published in the Scandinavian Journal of Gastroenterology, Volume 41, Number 4, March 2006 , pp. 408-419(12)

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines
Authors: Drago, Sandro1; El Asmar, Ramzi2; Di Pierro, Mariarosaria1; Grazia Clemente, Maria2; Sapone, Amit Tripathi Anna2; Thakar, Manjusha2; Iacono, Giuseppe3; Carroccio, Antonio3; D'Agate, Cinzia4; Not, Tarcisio5; Zampini, Lucia1; Catassi, Carlo1; Fasano, Alessio2
1: Dipartimento Scienze Materno-Infantile, Universita' Politecnico delle Marche, Ancona, Italy 2: Mucosal Biology Research Center, Center for Celiac Research and Division of Pediatric Gastroenterology and Nutrition, University of Maryland, School of Medicine, Baltimore, USA 3: Clinica Medica, Policlinico Università di Palermo, Palermo, Italy 4: Cattedra di Gastroenterologia, Azienda Ospedaliero Universitaria Policlinico-Univerita' degli Studi di Catania, Catania, Italy 5: Clinica Pediatrica Universita' di Trieste and IRCCS Bo Garofolo Trieste, Italy

This study can be accessed at: http://www.ingentaconnect.com/content/apl/sgas/2006/00000041/00000004/art00007;jsessionid=1acnoimmvf8go.alexandra

Based on the results of the study, the authors concluded that the gliadin part of gluten leads to increased intestinal damage in celiacs AND non-celiacs.

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Gluten causing bleeding into the lungs

Published in the Arch Dis Child. 1987 May;62(5):513-5.

Pulmonary haemosiderosis and gluten.
Reading R, Watson JG, Platt JW, Bird AG.

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/3606190
 
Gluten was found to be causing bleeding into the lungs in a child, requiring him to have monthly blood transfusions.
 
During 15 months on a gluten free diet his growth and behaviour improved and he required no transfusions.

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Gluten in the diet is associated with retarded teeth enamel; retarded growth; arthritis and other immunologic diseases; association with diabetes, allergies, gastrointestinal deficiencies, and probably Down's syndrome

Published in the Pediatr Clin North Am. 1988 Feb;35(1):157-87.

Gluten-sensitive enteropathy in childhood.
Auricchio S, Greco L, Troncone R.
Department of Pediatrics, University of Naples, Italy.

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/3277130
 
For celiac children the author observed that gluten in the diet is associated with retarded teeth enamel; retarded growth; arthritis and other immunologic diseases; association with diabetes, allergies, gastrointestinal deficiencies, and probably Down's syndrome.
 
Auricchio added: "Celiac children do require a permanent gluten-free (and not poor) diet. In reality, too many celiac adolescents are off-diet".

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More exposure to gluten results in more disease

Published in Gastroenterology. 1999 Aug;117(2):297-303.

Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disorders in Celiac Disease.
Ventura A, Magazzù G, Greco L.
Department of Pediatrics, University of Trieste, IRCCS Burlo-Garofolo, Trieste, Italy. ventura@burlo.trieste.it

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10419909
 
The data shows for the first time that the longer celiac disease sufferers are exposed to gluten the more disorders they suffer.

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Cutting out bread cures celiac disease

Published in JAMA. 1964;188(1):42-44.

Gluten-Free Diet for Nontropical Sprue
Julian M. Ruffin, MD; Stanley M. Kurtz, MD; James L. Borland, Jr, MD; Callum R. W. Bain, MD; Waguih M. Roufail, MD

This paper can be accessed at: http://jama.ama-assn.org/cgi/content/summary/188/1/42

In World War II in Holland it was observed that when bread was scarce or unobtainable, children having celiac disease improved clinically—their diarrhea ceased and they began to gain weight.

After the war, when bread became available these same children relapsed. It was shown that the material responsible was the gliadin fraction of gluten.

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