The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).
My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.
David Evans
Independent Health Researcher
Showing posts with label Saturated Fat and Cancer. Show all posts
Showing posts with label Saturated Fat and Cancer. Show all posts
This study investigated the association of dietary fat and the risk of pancreatic cancer. The study included 111,416 participants, aged 55 to 74 years, who were followed for 8.4 years.
The study found: (a) Those who consumed the most dietary fat had a 30% reduced risk of pancreatic cancer compared to those who consumed the least dietary fat. (b) Those who consumed the most saturated fat had a 36% reduced risk of pancreatic cancer compared to those who consumed the least saturated fat.
This study investigated the relationship between diet and prostate cancer. The study included 25,708men aged 16-56 years who were followed for up to 15 years.
The study found:
(a) Men who consumed the most saturated fat had a 30% reduced risk of prostate cancer compared to men who consumed the least saturated fat.
(b) Men who consumed the most meat had a 60% reduced risk of prostate cancer compared to men who consumed the least meat.
(c) Men who drank whole milk had a 120% reduced risk of prostate cancer compared to men who drank skimmed milk.
(d) Men who consumed the most polyunsaturated fat had a 40% increased risk of prostate cancer compared to men who consumed the least polyunsaturated fat.
(e) Men who drank skimmed milk had a significantly higher body mass index compared to men who drank whole milk.
The study suggests that a high saturated fat and meat consumption lowers the risk of prostate cancer.
This study assessed the association between fat intake and colorectal cancer. The study included 1,163 subjects with colon cancer and 1,501 healthy control subjects.
The study found:
(a) Those who consumed the most fat had a 16% decreased risk of colon cancer compared to those who consumed the least fat.
(b) Those who consumed the most saturated fat had a 5% decreased risk of colon cancer compared to those who consumed the least saturated fat.
The data from the study shows that a higher consumption of fat is associated with lower rates of colon cancer.
The study investigated the association of dietary fat consumption with the risk of breast cancer. The dietary histories of 18,586 postmenopausal women were analysed over a seven year period.
Regarding saturated fat consumption, the study found that for every 10 gram per day increase in saturated fat there was a 10% reduction in the risk of breast cancer.
This study was published in Cancer Research1994 May 1;54(9):2390-7
Study title and authors: Intake of fat, meat, and fiber in relation to risk of colon cancer in men.
Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Willett WC.
Channing Laboratory, Department of Medicine, Harvard Medical School, Boston, Massachusetts.
The study investigated the relationship of food intake with colon cancer. The six year study included 47,949 U.S. male health professionals (aged 40 to 75) who were free of cancer at the start of the study.
With regard to saturated fat, the study found those who consumed the most had a 12% decreased risk of colon cancer compared to those who consumed the least.
The study examined the relationship between meat and fat and squamouscellcancer of the esophagus (cancer that begins in flat cells lining the esophagus). The study included 82 cases with esophageal cancer and 248 controls.
The study found: (a) Those who ate the most beef had a 56% decreased risk of esophageal cancer compared to those who ate the least beef. (b) Those who ate the most saturated fat had a 73% decreased risk of esophageal cancer compared to those who ate the least saturated fat. (c) Those who ate the most polyunsaturated fat (margarines etc.) had a 219% increased risk of esophageal cancer compared to those who ate the least polyunsaturated fat.
The results from the study show that beef and saturated fat decrease the risk of esophageal cancer.
This study was published in the American Journal of Epidemiology2004 Nov 15;160(10):1011-22
Study title and authors:
Dietary fat and fatty acids and risk of colorectal cancer in women.
Lin J, Zhang SM, Cook NR, Lee IM, Buring JE.
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215, USA. jhlin@rics.bwh.harvard.edu
Dr. Jennifer Lin, an Assistant Professor of Medicine at the Harvard Medical School, examined the association of intakes of different types of fat with the risk of colon cancer. She and her colleagues analyzed the diets of 37,547 women over 8.7 years.
Dr. Lin found:
Women who consumed the most saturated fat had an 8% reduced incidence of colon cancer compared to the women who ate the least.
Women who consumed the most cholesterol had a 21% reduced incidence of colon cancer compared to the women who ate the least.
Women who consumed the most red meat had a 34% reduced incidence of colon cancer compared to the women who ate the least.
Women who consumed the most vegetable fat had a 21% increased incidence of colon cancer compared to the women who ate the least.
This study shows that dietary cholesterol, animal fats and red meat give protection from colon cancer, whereas vegetable fats (margarine, sunflower oil etc.) increase the risk of colon cancer.
This study was published in the Journal of the National Cancer Institute1998 Nov 18;90(22):1710-9
Study title and authors:
Dietary and nutritional factors and pancreatic cancer: a case-control study based on direct interviews.
Silverman DT, Swanson CA, Gridley G, Wacholder S, Greenberg RS, Brown LM, Hayes RB, Swanson GM, Schoenberg JB, Pottern LM, Schwartz AG, Fraumeni JF Jr, Hoover RN.
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. silvermd@EPNDCE.NCI.NIH.GOV
This study investigated the relationship between diet and pancreatic cancer in 436 patients and 2003 general-population control subjects aged 30-79 years.
The study found:
Those who had the lowest consumption of bread, grains and cereals had an 8% decreased rate of pancreatic cancer compared to those who had the highest consumption of bread, grains and cereals.
Those who had the lowest consumption of carbohydrates had a 36% decreased rate of pancreatic cancer compared to those who had the highest consumption of carbohydrates.
Those who ate the most fat had a 34% decreased rate of pancreatic cancer compared to those who ate the least fat.
Those who ate the most saturated fat had a 28% decreased rate of pancreatic cancer compared to those who ate the least saturated fat.
Those who ate the most red meat had an 18% decreased rate of pancreatic cancer compared to those who ate the least red meat.
This study shows that diets high in saturated fat and red meat offer protection from pancreatic cancer.
This post includes a synopsis of a study published in the New England Journal of Medicine 1987; 316:22-28 January 1 and a recipe for a steak marinade.
Study title and authors: Dietary Fat and the Risk of Breast Cancer
Walter C. Willett, M.D., Meir J. Stampfer, M.D., Graham A. Colditz, M.B., B.S., Bernard A. Rosner, Ph.D., Charles H. Hennekens, M.D., and Frank E. Speizer, M.D. Books: The study can be accessed at: http://www.nejm.org/doi/pdf/10.1056/NEJM198701013160105
The study assessed the intake of dietary fat and it's effect on breast cancer on 89,538 U.S. registered nurses who were 34 to 59 years of age over 4 years.
1/4 teaspoon white pepper
3 tablespoons freshly squeezed lemon juice
Directions:
Mix the marinade ingredients in a non-reactive pan. Score the meat, and place it in the pan and turn in the marinade. Marinate for at least 2 hours at room temperature or up to 24 hours refrigerated. If refrigerated, turn the steak in the marinade occasionally. Remove the steaks from the marinade (retain marinade) and grill to taste. Bring the remaining marinade to a boil in a non-reactive saucepan and remove from heat.
Carve the meat in thin diagonal slices across the grain (this makes for a tender cut) and arrange the slices on a warm platter. Pour the carving juices and the marinade over the meat. Decorate, if desired, with parsley sprigs or watercress.
The effects of monounsaturated, polyunsaturated and saturated fat on breast cancer were investigated on 61,471 women aged 40 to 76 years.
The results of the study revealed that:
(a) Those with the highest consumption of polyunsaturated fat had a 20% increase in breast cancer rates compared to those who consumed the least.
(b) Those with the highest consumption of monounsaturated fat had a 20% decrease in breast cancer rates compared to those who consumed the least.
(c) Saturated fat was not associated with the risk of breast cancer.
This post contains a synopsis of a study published in the American Journal of Clinical Nutrition 2005 Oct;82(4):894-900 and a recipe for crock pot pot roast.
Study title and authors: High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort.
Larsson SC, Bergkvist L, Wolk A.
Division of Nutritional Epidemiology, the National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. susanna.larsson@imm.ki.se
The aim of the study was to examine the associations of long-term high-fat dairy food consumption and conjugated linoleic acid (CLA) intake and the incidence of colorectal cancer. The study consisted of 60,708 women aged 40-76 years with over 14 years of follow-up.
The study found:
(a) Women who consumed 4 or more servings of high-fat dairy foods per day (including whole milk, full-fat cultured milk, cheese, cream, sour cream, and butter) had a 41% decreased risk of colorectal cancer when compared with the women who consumed less than 1 serving per day.
(b) Each increment of 2 servings of high-fat dairy foods per day corresponded to a 13% reduction in the risk of colorectal cancer.
(c) Women who consumed the most conjugated linoleic acid had a 29% reduction in the risk of colorectal cancer.
Conjugated linoleic acid can be found in animal based foods, including milk and meat. Different meats have higher levels of conjugated linoleic acid. Grass-fed cattle have a much higher amount of conjugated linoleic acid than grain-fed cattle. For this reason, grass-fed cattle and sheep may be the best source of conjugated linoleic acid.
1 lg onion, chopped
3 lg carrots, peeled and sliced
16 oz can diced tomatoes, undrained
Instructions:
Brown the roast on top of the stove beforehand, on all sides in a little olive oil.
Place the onion and carrots on the bottom of the crock pot (you'll need at least a 4 quart crock pot for this recipe). Put the meat on top and season to taste with salt and pepper. Pour the tomatoes over all and cook on low for 8 to 10 hours, or on high for 4 to 5 hours.
This post includes a synopsis of a study published in the British Medical Journal 2010 Jan 21;340:b5500 and a recipe for beef and chicken liver.
Study title and authors: Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study.
Books:
Jenab M, Bueno-de-Mesquita HB, Ferrari P, van Duijnhoven FJ, Norat T, Pischon T, Jansen EH, Slimani N, Byrnes G, Rinaldi S, Tjønneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, Kaaks R, Linseisen J, Boeing H, Bergmann MM, Trichopoulou A, Misirli G, Trichopoulos D, Berrino F, Vineis P, Panico S, Palli D, Tumino R, Ros MM, van Gils CH, Peeters PH, Brustad M, Lund E, Tormo MJ, Ardanaz E, RodrÃguez L, Sánchez MJ, Dorronsoro M, Gonzalez CA, Hallmans G, Palmqvist R, Roddam A, Key TJ, Khaw KT, Autier P, Hainaut P, Riboli E.
International Agency for Research on Cancer (IARC-WHO), Lyon, France. Jenab@iarc.fr
The study revealed that patients with highest vitamin D levels had a 40% lower risk of colorectal cancer than did those who had the lowest.
Exposure to sunlight allows us to produce vitamin D and the richest dietary sources include: butterfat, lard, eggs, liver, organ meats, marine oils and seafood.
This post contains a summary of a study published in Cancer epidemiology, biomarkers and prevention 2008 Oct;17(10):2800-7 and a recipe for chicken pancakes.
Study title and authors: Calcium, dairy foods, vitamin D, and colorectal cancer risk: the Fukuoka Colorectal Cancer Study.
Books:
Mizoue T, Kimura Y, Toyomura K, Nagano J, Kono S, Mibu R, Tanaka M, Kakeji Y, Maehara Y, Okamura T, Ikejiri K, Futami K, Yasunami Y, Maekawa T, Takenaka K, Ichimiya H, Imaizumi N.
Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. mizoue@ri.imcj.go.jp
This post features a chart showing butter consumption since 1926
The chart below plots butter consumption trends versus the incidence of cancer and heart disease. Since 1926, consumption of butter has dropped precipitously, at the same time cancer and heart disease has soared. Many factors may be involved as to what causes cancer and heart disease but for sure it’s not the consumption of butter because these trends are going in the opposite direction.