The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).
My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.
David Evans
Independent Health Researcher
Showing posts with label Insulin and Heart Disease. Show all posts
Showing posts with label Insulin and Heart Disease. Show all posts
Persistent Elevation of Plasma Insulin Levels Is Associated With Increased Cardiovascular Risk in Children and Young Adults. The Bogalusa Heart Study
Weihang Bao, PhD; Sathanur R. Srinivasan, PhD; Gerald S. Berenson, MD
From the Tulane National Center for Cardiovascular Health, Tulane School of Public Health and Tropical Medicine, New Orleans, La.
The study examined the influence of persistently elevated fasting insulin levels from childhood to young adulthood and their effects on heart disease risk factors such as obesity and blood pressure.
The study found that: As adults individuals with consistently elevated insulin versus those with consistently decreased insulin had increased prevalence of obesity (36-fold) and high blood pressure (2.5-fold).
Published in Diabetologia Volume 19, Number 3, 205-210
Relationship of plasma insulin levels to the incidence of myocardial infarction and coronary heart disease mortality in a middle-aged population
P. Ducimetiere, E. Eschwege, L. Papoz, J. L. Richard, J. R. Claude and G. Rosselin
The study investigated the possible role of insulin levels as a risk factor of heart disease. The study included 7,246 non diabetic, working men, aged 43–54 years, initially free from heart disease, and followed for 63 months on average.
Ducimetiere found that insulin levels were associated with heart disease and concluded: "high insulin levels may constitute an independent risk factor for coronary heart disease complications in middle aged non diabetic men".
This post features a synopsis of a study published in Metabolism Volume 32, Issue 1, January 1983, Pages 52-56 and a recipe for a lamb curry.
Study title and authors: Plasma glucose, insulin and lipid responses to high-carbohydrate low-fat diets in normal humans*1
Ann M. Coulstonb, a, George C. Liub, a and Gerald M. Reaven, a, b,
a Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA.
b Veterans Administration Medical Center, Palo Alto, California, USA.
Corresponding author. Address reprint requests to Dr. Gerald M. Reaven, Department of Medicine, Geriatric Research, Education and Clinical Center, Rm. 182B, Veterans Administration Medical Center, 3801 Miranda Avenue, Palo Alto, CA 94304.
*1 Supported in part by the Research Services of the Veterans Administration, the General Clinical Research Centers Branch of the NIH (RR-70) and by NIH Grant HL-08506.
The study investigated the effects of two diets. One at 40% carbohydrate of calories (Lower Carb), the other at 60% carbohydrate of calories (Higher Carb). Insulin, triglyceride (TG) and high density lipoprotein (HDL)-cholesterol concentrations were analysed. Books:
The study found that:
(a) (Bad) Triglyceride levels were increased on the higher carb diet.
(b) (Bad) Insulin levels were increased on the higher carb diet.
(c) (Good) HDL-cholesterol concentrations were decreased on the higher carb diet.
The authors conclude: "These results indicate that high-carbohydrate diets lead to changes in insulin, TG, and HDL-cholesterol concentrations which have been associated with an increase in incidence of coronary artery disease".
Ingredients:
2 T coconut oil Food Mall: Boneless Lamb
1 lb cubed lamb meat or lamb stew meat
1 large or 2 medium onions
3-4 carrots
1 T grated ginger root
3 cloves of garlic
2 tsp curry powder
1 tsp salt
1/2 c broth
1 c coconut milk
Method:
Cut the onion into large pieces and chop the carrots into 1-inch lengths, set aside.
Melt the coconut oil in a large pot and brown the meat. Remove the meat and set aside, leaving the fat in the pan.
Saute the onions on mediumuntil they soften, about 10 minutes. Then add the garlic, ginger, and curry powder and saute a little longer. Add the carrots and continue to stir to coat them with the spice mixture.
Pour in the stock and scrape up any brown bits that are still stuck to the bottom of the pan from browning the meat. Pour in the coconut milk and bring to a simmer.
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. See 
lead to changes in insulin, TG, and HDL-cholesterol concentrations which have been associated with an increase in incidence of coronary artery disease".
